CONTRIBUTION OF ERRORS INDUCED BY THE TAQ POLYMERASE TO ESTIMATE THE DIVERSITY OF RNA VIRUS.

The genetic diversity of a vesicular stomatitis virus population was analyzed by RT-PCR, cloning and sequencing of about 500 nucleotide regions of the virus genome. PCR amplifications were performed in parallel experiments with DNA Taq and PFU polymerases and significant differences were observed. Between 10 and 22 mutations were detected when virus populations were analyzed by TAQ amplification (20 clones of each region), while the amplification of the same samples with PFU revealed between 0 and 5 mutations. PCR loyalty tests, carried out under the same PCR conditions as those used in the population analysis, have shown that the Taq error rate estimation of 0.27 x 10 (-4) Enporations by PB by Cycle was included in the range estimated elsewhere of the amplification of the recombinant PCR plasmids (0.27-0.85 x 10 (-4) Errors by BP per cycle) or functional tests (0.2-2 x 10 ( -4) Errors by PB per cycle).

The TAQ error rate has been found to be 9.3 times higher than the PFU error rate with DNA as a model, and about 10 times higher with the CDNCs obtained by inverse transcription of models. Viral RNA from natural populations. In this study, we discuss (i) the implications of TAQ errors on the analysis of genetic variability, based on both frequency and nature (synonymous replacement) of the substitutions observed and (ii) the size of the Sample required to evaluate genetics variability in a virus population generated by a single infection. In this project, a real-time polymerase chain reaction (PCR) was used to study the mechanism of PCR inhibition by examining the effect of the amplicon length, the melting temperature and of the sequence.

First specially designed with three different amplicon lengths and three different melting temperatures have been used to target a single homozygous allele in the Humert01 locus. The effect on the efficiency of the amplification of each pair of primers has been determined by adding different concentrations of various PCR inhibitors to the reaction mixture. The results show that various inhibition mechanisms can occur during the PCR process based on the type of co-extract inhibitor. These include TAQ inhibition, the binding of DNA templates and the effects on the efficiency of the reaction.

PCR-resistant PCR-resistant Taq DNA mutants allow for amplification of total blood DNA and gross soil samples.

Powerful PCR inhibitors in blood and soil samples can cause false negative results of PCR-based clinical and lawy tests. We show that the effect of these inhibitors is mainly on the TAQ DNA polymerase, because the mutational modification of the polymerase can overcome the inhibition insofar as no purification of the DNA is now required. N-terminal removal (Klentaq1) is an inhibition of 10 to 100 times resistant to total blood relative to the Taq Wild Type TAQ (W.T.) Taq, which is strongly inhibited by 0.1 to 1% blood. Other mutations at Codon 708, both in Klentaq 1 and Taq, give increased resistance to various PCR reaction inhibitors, including total blood, plasma, hemoglobin, lactoferrin, IgG. Serum, soil extracts and humic acid, as well as high concentrations of inserted dyes.

The blood PCR inhibitors can mainly reduce the speed of extension of the W.T DNA Taq polymerase with respect to mutant enzymes. Human genomic targets to a human copy are easily amplified from total blood or raw soil extract, without pretreatment to purify the template DNA, and the permitted increase in the dye concentration overcomes the background of Fluorescence and quenching in real-time blood PCR.

CONTRIBUTION OF ERRORS INDUCED BY THE TAQ POLYMERASE TO ESTIMATE THE DIVERSITY OF RNA VIRUS.
CONTRIBUTION OF ERRORS INDUCED BY THE TAQ POLYMERASE TO ESTIMATE THE DIVERSITY OF RNA VIRUS.

DNA removal contaminant in the reaction reagents of the polymerase chain: implications for a general approach to the detection of unutaneous pathogens.

The analysis based on comparisons of RNA 16S sequences provides a quick and reliable approach to identifying human pathogens. By leading the primers of oligonucleotides to the sequences preserved throughout the kingdom of ebacterial, the bacterial ribosomal DNA sequences of substantially any member of the kingdom of the ebacteria can be amplified by the reaction of the chain of the polymerase and subsequently analyzed by the determination of the sequence. Indeed, automated wide range amplification systems, sequencing and data analysis are now feasible and can be founded on the next generation of automated microbial identification systems.

However, the identification of the pathogens by this strategy is hampered by the frequent contamination of the reagents used for the amplification reaction, in particular the Taq polymerase, with an exogenous bacterial DNA. Here, we describe detailed surveys of the use of 8-methoxypsorane UV light and the long waves to remove the contaminant DNA in the reaction reagents of the polymerase chain. The clinical utility of the developed procedure has been demonstrated in a case of pacifacillary osteomyelitis for which no specific bacterial agent had been cultivated. We have developed and characterized a test for the interactive compounds of G-quadruplex that use the fact that G-rich DNA models have barriers to the synthesis of DNA by DNA polymerases.

Recombinant Measles Virus MV Large Polymerase 58-149 a. a Protein, Untagged, E.coli-500ug

QP12758-500ug 500ug
EUR 795.6

Recombinant (E.Coli) Measles Virus Large Polymerase (58-149)

RP-651 100 ug
EUR 343.2

Recombinant (E.Coli) purified Measles virus Large Polymerase (58-149)

RP-1613 100 ug
EUR 416.4

Recombinant MeV Active Large Polymerase Protein (aa 58-149)

VAng-Lsx0397-inquire inquire Ask for price
Description: Measles Active Large Polymerase protein (aa 58-149), recombinant protein from E. coli.

Recombinant MeV Polymerase Protein (aa 58-149)

VAng-Lsx0394-inquire inquire Ask for price
Description: MeV Polymerase (aa 58-149), recombinant protein from E. coli.

EM (Anti-endometrial Antibody IgA) ELISA test

58 96T/Box Ask for price
Description: ELISA based test for quantitative detection of EM (Anti-endometrial Antibody IgA)

Bst DNA Polymerase Large Fragment

P701-01 800 U
EUR 146.4

Bst DNA Polymerase Large Fragment

P701-02 8000 U
EUR 325.2

Recombinant MeV Large Polymerase Protein

VAng-Lsx0385-inquire inquire Ask for price
Description: Recombinant MeV Large Polymerase containing the large polymerase immunodominant regions, 58-149 amino acids was expressed in E. coli and purified by proprietary chromatographic technique.

Bst DNA Polymerase, Large Fragment

M1213-200 each
EUR 346.8

Bsu DNA Polymerase Large Fragment

M1214-200 each
EUR 477.6

Recombinant HPV-58 E6 (aa 1-149) Protein

VAng-Wyb3337-1mgEcoli 1 mg (E. coli)
EUR 3789.6
Description: Human papillomavirus type 58 protein E6, recombinant protein.

Recombinant HPV-58 E6 (aa 1-149) Protein

VAng-Wyb3337-500gEcoli 500 µg (E. coli)
EUR 2700
Description: Human papillomavirus type 58 protein E6, recombinant protein.

Recombinant HPV-58 E6 (aa 1-149) Protein

VAng-Wyb3337-50gEcoli 50 µg (E. coli)
EUR 1858.8
Description: Human papillomavirus type 58 protein E6, recombinant protein.

Mouse pre-microRNA Expression Construct mir-149

MMIR-149-PA-1 Bacterial Streak
EUR 820.8

DNA Polymerase I Large (Klenow) Fragment

M1212-100 each
EUR 333.6

Recombinant Measles Virus Large Polymerase (2059-2183)

7-07843 100µg Ask for price

Recombinant Measles Virus Large Polymerase (2059-2183)

7-07844 500µg Ask for price

Recombinant Measles Virus Large Polymerase (2059-2183)

7-07845 1000µg Ask for price

Measles Virus Large Polymerase (2059-2183) Protein

20-abx260297
  • EUR 1062.00
  • EUR 410.40
  • EUR 1930.80
  • 0.5 mg
  • 100 ug
  • 1 mg

Cyanine 3.5 Maleimide [equivalent to Cy3.5® Maleimide]

149 1 mg
EUR 367.2

Cenarchaeum symbiosum DNA polymerase II large subunit (polC)

1-CSB-EP370095DRA
  • EUR 745.20
  • EUR 457.20
  • EUR 2331.60
  • EUR 1058.40
  • EUR 1602.00
  • EUR 541.20
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Cenarchaeum symbiosum DNA polymerase II large subunit(polC),partial expressed in E.coli

DNA Polymerase I, Large (Klenow) Fragment - 1,000 units

3262 1/EA
EUR 346.8

Recombinant (E.Coli) Measles Virus Large Polymerase (2059-2183)

RP-653 100 ug
EUR 343.2

Recombinant (E.Coli) purified Measles virus Large Polymerase (2059-2183)

RP-1612 100 ug
EUR 416.4

Recombinant MeV Active Large Polymerase Protein (aa 2059-2183)

VAng-Lsx0399-inquire inquire Ask for price
Description: Measles Active Large Polymerase protein (aa 2059-2183), recombinant protein from E. coli.

ph/mv/ion/o2 module

D291 ea
EUR 778.8

Human morbillivirus,MV ELISA Kit

201-12-1791 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human morbillivirus(MV)ELISA Kit

GA-E1807HM-48T 48T
EUR 346.8

Human morbillivirus(MV)ELISA Kit

GA-E1807HM-96T 96T
EUR 559.2

Human morbillivirus(MV)ELISA Kit

QY-E02207 96T
EUR 433.2

Canine morbillivirus,MV ELISA KIT

QY-E70150 96T
EUR 511.2

Seven2Go S2 pH/mv meter

PHM0013 EACH
EUR 474.24

GANT 58

A3429-10 10 mg
EUR 172.8
Description: GANT 58 is an antagonist of GLI that inhibits GLI1-induced transcription with an IC50 value of 5 ?M [1]. GLI1 is a human glioblastoma isolated protein which belongs to GLI protein family.

GANT 58

A3429-100 100 mg
EUR 644.4
Description: GANT 58 is an antagonist of GLI that inhibits GLI1-induced transcription with an IC50 value of 5 ?M [1]. GLI1 is a human glioblastoma isolated protein which belongs to GLI protein family.

GANT 58

A3429-5 5 mg
EUR 130.8
Description: GANT 58 is an antagonist of GLI that inhibits GLI1-induced transcription with an IC50 value of 5 ?M [1]. GLI1 is a human glioblastoma isolated protein which belongs to GLI protein family.

GANT 58

A3429-5.1 10 mM (in 1mL DMSO)
EUR 145.2
Description: GANT 58 is an antagonist of GLI that inhibits GLI1-induced transcription with an IC50 value of 5 ?M [1]. GLI1 is a human glioblastoma isolated protein which belongs to GLI protein family.

GANT 58

A3429-50 50 mg
EUR 459.6
Description: GANT 58 is an antagonist of GLI that inhibits GLI1-induced transcription with an IC50 value of 5 ?M [1]. GLI1 is a human glioblastoma isolated protein which belongs to GLI protein family.

DASA-58

B6025-25 25 mg
EUR 525.6
Description: DASA-58 is an selective activator of pyruvate kinase M2 (PKM2) with an AC90 value of 680 nM, and an AC50 value of 38 nM [1].In cancer, the altered glucose metabolism can be influenced by the regulatory properties of PKM2.

DASA-58

B6025-5 5 mg
EUR 205.2
Description: DASA-58 is an selective activator of pyruvate kinase M2 (PKM2) with an AC90 value of 680 nM, and an AC50 value of 38 nM [1].In cancer, the altered glucose metabolism can be influenced by the regulatory properties of PKM2.

Brij 58

B6306 250g
EUR 260.1

GV-58

HY-12498 5mg
EUR 555.6

GANT 58

HY-13282 10mM/1mL
EUR 160.8

DASA-58

HY-19330 100mg
EUR 1879.2

DASA-58

B2163-1 each
EUR 157.2

DASA-58

B2163-5 each
EUR 444

GV-58

2616-1 each
EUR 183.6

GV-58

2616-5 each
EUR 548.4

MG 149

B3276-100 100 mg
EUR 1004.4
Description: MG 149 is an inhibitor of histone acetyltransferases (HAT) with IC50 values of 74?M and 47?M for Tip60 and MOF, respectively [1].MG 149 is an anacardic acid derivative.

MG 149

B3276-25 25 mg
EUR 524.4
Description: MG 149 is an inhibitor of histone acetyltransferases (HAT) with IC50 values of 74?M and 47?M for Tip60 and MOF, respectively [1].MG 149 is an anacardic acid derivative.

MG 149

B3276-5 5 mg
EUR 201.6
Description: MG 149 is an inhibitor of histone acetyltransferases (HAT) with IC50 values of 74?M and 47?M for Tip60 and MOF, respectively [1].MG 149 is an anacardic acid derivative.

MG 149

HY-15887 50mg
EUR 1250.4

Pig Cholecystokinin 58 (CCK-58) ELISA Kit

abx361664-96tests 96 tests
EUR 990

IFNG a.a. Interferon-gamma 139 a.a Human Recombinant Protein

PROTP01579-2 Regular: 10ug
EUR 380.4
Description: IFNG 139 a.a. Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 139 amino acids (24-161 a.a.) and having a molecular mass of 16.3kDa.; IFNG 139 a.a. is purified by proprietary chromatographic techniques.

FiveGo F2 pH/mV F2-Meter

PHM0028 EACH
EUR 340.86

FiveGo F2 pH/mV F2-Standard

PHM0029 EACH
EUR 482.22

FiveGo F2 pH/mV F2-Food

PHM0030 EACH
EUR 533.52

FiveGo F2 pH/mV F2-Field

PHM0031 EACH
EUR 539.22

miRZip-149 anti-miR-149 microRNA construct

MZIP149-PA-1 Bacterial Streak
EUR 820.8

IL36A a.a. Interleukin-36 Alpha 153 a.a Mouse Recombinant Protein

PROTQ9JLA2-1 Regular: 10ug
EUR 380.4
Description: IL36A 153 a.a. Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 153 amino acids (8-160a.a.) and having a molecular mass of 17.0kDa.;The IL36A 153 a.a. Mouse is purified by proprietary chromatographic techniques.

IL36B a.a. Interleukin-36 Beta 153 a.a Human Recombinant Protein

PROTQ9NZH7-1 Regular: 10ug
EUR 380.4
Description: IL36B 153 a.a. Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 153 amino acids (5-157a.a.) and having a molecular mass of 17.2kDa.;The IL36B 153 a.a. Human is purified by proprietary chromatographic techniques.

IL36G a.a. Interleukin-36 Gamma (152 a.a) Human Recombinant Protein

PROTQ9NZH8-1 Regular: 10ug
EUR 380.4
Description: IL36G (152 a.a.) Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 152 amino acids and having a molecular mass of 17.0kDa.;The IL36G (152 a.a.) is purified by proprietary chromatographic techniques.

CGI-58 Antibody

3901-100 each
EUR 379.2

CGI-58 Antibody

3901-30T each
EUR 175.2

HBcAg (a.a. 80) Antibody

abx021791-100ug 100 ug
EUR 678

ITLN1 298 a.a. Protein

20-abx260698
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

IL16 (121 a.a.) Protein

20-abx262189
  • EUR 393.60
  • EUR 6991.20
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

IL13 109 a.a. Protein

20-abx262191
  • EUR 393.60
  • EUR 6991.20
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

IL16 (130 a.a.) Protein

20-abx262202
  • EUR 393.60
  • EUR 6991.20
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

IL36G 152 a.a. Protein

20-abx262383
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

IL36A 158 a.a. Protein

20-abx262384
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

IL36B 153 a.a. Protein

20-abx262385
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

IL36A 153 a.a. Protein

20-abx262386
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

HIF1a (85 a.a.) Protein

20-abx263442
  • EUR 276.00
  • EUR 1930.80
  • EUR 393.60
  • 1 µg
  • 50 ug
  • 5 ug

LARGE antibody

70R-6856 50 ug
EUR 560.4
Description: Rabbit polyclonal LARGE antibody raised against the middle region of LARGE

LARGE Peptide

42-560P 0.1 mg
EUR 405.6
Description: (IN) LARGE Peptide

LARGE Peptide

42-561P 0.1 mg
EUR 405.6
Description: (NT) LARGE Peptide

LARGE siRNA

20-abx922269
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

LARGE siRNA

20-abx922270
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

Platform Large

MIX1340 EACH
EUR 103.74

Large Compressor

AAQ525 EACH
EUR 2397.42

LARGE Antibody

R35864-100UG 100 ug
EUR 399

MV (Measles Virus Antibody IgG) ELISA test

142 96T/Box Ask for price
Description: ELISA based test for quantitative detection of MV (Measles Virus Antibody IgG)

MV (Measles Virus Antibody IgM) ELISA test

143 96T/Box Ask for price
Description: ELISA based test for quantitative detection of MV (Measles Virus Antibody IgM)

Human measlesvirus IgM,MV IgM ELISA kit

201-12-1765 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human measlesvirus IgG,MV IgG ELISA Kit

201-12-1773 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

redox standard solution 50 ml 124 mv

B071 ea
EUR 26.4

redox standard solution 50 ml 358 mv

B072 ea
EUR 26.4

redox standard solution 500 ml 124 mv

B571 ea
EUR 43.2

redox standard solution 500 ml 358 mv

B572 ea
EUR 43.2

Human measlesvirus IgM(MV IgM)ELISA Kit

GA-E1781HM-48T 48T
EUR 346.8

Human measlesvirus IgM(MV IgM)ELISA Kit

GA-E1781HM-96T 96T
EUR 559.2

Human measlesvirus IgG(MV IgG)ELISA Kit

GA-E1789HM-48T 48T
EUR 346.8

Human measlesvirus IgG(MV IgG)ELISA Kit

GA-E1789HM-96T 96T
EUR 559.2

Human measlesvirus IgM(MV IgM)ELISA Kit

QY-E02205 96T
EUR 433.2

Human measlesvirus IgG(MV IgG)ELISA Kit

QY-E02206 96T
EUR 433.2

METTLER TOLEDO FIVEGO(TM) PH / MV PORTA

MT30266882-1EA EACH
EUR 539.22

Seven2Go S2 Stnd Kit pH/mv meter

PHM0014 EACH
EUR 592.8

Seven2Go S2 Field Kit pH/mv meter

PHM0015 EACH
EUR 644.1

Seven2Go S2 Food Kit pH/mv meter

PHM0016 EACH
EUR 689.7

Seven2Go S2 Light Kit pH/mv meter

PHM0017 EACH
EUR 524.4

Recombinant Human C1QL4 Protein

CTP-149 100ug Ask for price
Description: A recombinant human C1QL4 protein with a N-terminal tag or C-terminal tag expressed in E. Coli, yeast, insect, or mammalian cell.

Native Microorganism Glycerol Kinase

DIA-149 10 KU
EUR 402

Rac1 Recombinant Adenovirus

ADV-149 50 ?L
EUR 1069.2
Description: Premade recombinant adenovirus containing the Rac1 gene

Retinol-Binding Protein 4 Recombinant Protein

91-149 0.05 mg
EUR 556.8
Description: Retinol Binding Protein 4 (RBP4) is a member of the Lipocalin family and in the blood. RBP4 is the specific vector for retinol. RBP4 is expressed and secreted by adipose tissue, and is associated with insulin resistance. RBP4 delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin to prevents its loss by filtration through the kidney glomeruli. Defects in RBP4 cause retinol-binding protein deficiency and can cause night vision problems.

Carbonic Anhydrase 14 Recombinant Protein

92-149 0.05 mg
EUR 852.9
Description: Carbonic Anhydrase 14 (CA14) belongs to the Alpha-Carbonic Anhydrase family. It is highly expressed in all parts of the central nervous system and lowly expressed in adult liver, heart, small intestine, colon, kidney, urinary bladder, and skeletal muscle. CA14 along with other Carbonic Anhydrases (CAs) participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA14 is predicted to be a type I membrane protein and catalyzes the reversible hydration of carbon dioxide.

4-1BB / TNFRSF9 Recombinant Protein

11-149 0.1 mg
EUR 714.3
Description: 4-1BB is also known as CD137, tumor necrosis factor receptor superfamily member 9 (TNFRSF9), induced by lymphocyte activation (ILA), is a co-stimulatory molecule of the tumor necrosis factor (TNF) receptor superfamily. CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. The best characterized activity of CD137 is its costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice. CD137 can enhance activation-induced T cell apoptosis when triggered by engagement of the TCR/CD3 complex. In addition, 4-1BB/4-1BBL co-stimulatory pathway has been shown to augment secondary CTL responses to several viruses, and meanwhile augment anti-tumor immunity. 4-1BB thus is a promising candidate for immunotherapy of human cancer. CD137 has been shown to interact with TRAF2.

CTRP5 Recombinant Protein

90-149 50 ug
EUR 852.9
Description: CTRP5 (C1qTNF-related protein 5; C1QTNF5) belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD).

Monkey (Cynomolgus) cDNA Normal Tissue: Liver

MC34-149 10 rxn
EUR 498

Tris-HCl Molecular/Proteomic Grade

18-149 500g/Unit
EUR 327

a.a.), TRAIL/APO 2 Ligand (114-281 a.a.) Human Recombinant Protein, Active

PROTP50591-2 Regular: 10ug
EUR 380.4
Description: Soluble TNF-related apoptosis-inducing ligand Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 169 amino acids _x000D_ (114-281) and having a molecular mass of 19.6 kDa._x000D_ The sTRAIL is purified by proprietary chromatographic techniques.

Recombinant Human Omentin 298 a.a.

7-01318 5µg Ask for price

Recombinant Human Omentin 298 a.a.

7-01319 20µg Ask for price

Recombinant Human Omentin 298 a.a.

7-01320 1mg Ask for price

HBcAg (a.a. 1-10) Antibody

abx021792-100ug 100 ug
EUR 678

HBcAg (a.a. 130-140) Antibody

abx021793-100ug 100 ug
EUR 678

HBcAg (a.a. 135-140) Antibody

abx021794-100ug 100 ug
EUR 661.2

HBcAg (a.a. 138-145) Antibody

abx021796-100ug 100 ug
EUR 693.6

HBcAg (a.a. 70-80) Antibody

abx021797-100ug 100 ug
EUR 693.6

Ubiquitin (A.A. 50-65) Antibody

abx023804-01ml 0.1 ml
EUR 1663.2

Streptavidin (37-159 a.a) Protein

20-abx261085
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Adiponectin (108-244 a.a.) Protein

20-abx261717
  • EUR 4236.00
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Use of Taq DNA polymerase and G-quadruplex 2, 6-diamidoantoanthraquinone bonding BSU-1051, we find that the BSU-1051 leads to improved arrest of the synthesis of the DNA in the presence of K + by stabilizing an intramolecular structure G-quadruplex formed by four repetitions of TTGGGG or TTAGGG in the model pane. The data provides additional evidence that BSU-1051 modules the telomerase activity by stabilizing G-quadruple telomer DNA and point to a polymerase stop test as a sensitive method for screening for interactive agents of G- Quadruplex with potential clinical utility.