Spike (S) Protein

Lab Reagents

Human IgG antibody Laboratories manufactures the spike (s) protein reagents distributed by Genprice. The Spike (S) Protein reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact Spike Protein. Other Spike products are available in stock. Specificity: Spike Category: (S) Group: Protein

Protein information

Recombinant SARS Associated Spike Mosaic S(M)

7-07096 100µg Ask for price

Recombinant SARS Associated Spike Mosaic S(M)

7-07097 500µg Ask for price

Recombinant SARS Associated Spike Mosaic S(M)

7-07098 1000µg Ask for price

Recombinant SARS Associated Spike Mosaic S©

7-07099 100µg Ask for price

Recombinant SARS Associated Spike Mosaic S©

7-07100 500µg Ask for price

Recombinant SARS Associated Spike Mosaic S©

7-07101 1000µg Ask for price

Recombinant (E.Coli) SARS Associated Spike Mosaic S

RP-1422 100 ug
EUR 286

Recombinant (E.Coli) SARS Associated Spike Mosaic S

RP-1423 100 ug
EUR 286

Recombinant (E.Coli) SARS Associated Spike Mosaic S

RP-1424 100 ug
EUR 286

Recombinant Coronavirus Spike Protein (SARS-CoV S, His tag)

P1520-10 10µg
EUR 257

SARS-CoV-2 (COVID-19) Trimeric Spike (S) Recombinant Protein

10-075 0.1 mg
EUR 826.25
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is an enveloped, single-stranded, positive-sense RNA virus that belongs to the Coronaviridae family 1. The SARS-CoV-2 genome, which shares 79.6% identity with SARS-CoV, encodes four essential structural proteins: the spike (S), envelope (E), membrane (M), and nucleocapsid protein (N) 2. The S protein is a transmembrane, homotrimeric, class I fusion glycoprotein that mediates viral attachment, fusion, and entry into host cells 3. Each ~180 kDa monomer contains two functional subunits, S1 (~700 a.a) and S2 (~600 a.a), that mediate viral attachment and membrane fusion, respectively. S1 contains two major domains, the N-terminal (NTD) and C-terminal domains (CTD). The CTD contains the receptor-binding domain (RBD), which binds to the angiotensin-converting enzyme 2 (ACE2) receptor on host cells 3-5. Although both SARS-CoV and SARS-CoV-2 bind the ACE2 receptor, the RBDs only share ~73% amino acid identity, and the SARS-CoV-2 RBD binds with a higher affinity compared to SARS-CoV 3, 6. The RBD is dynamic and undergoes hinge-like conformational changes, referred to as the “down” or “up” conformations, which hide or expose the receptor-binding motifs, respectively 7. Following receptor binding, S1 destabilizes, and TMPRSS2 cleaves S2, which undergoes a pre- to post-fusion conformation transition, allowing for membrane fusion 8, 9. The S protein has been the main focus of therapeutic and vaccine design as it is highly immunogenic. Both neutralizing antibodies 10,11 and memory T cells 12,13 targeting the S protein are present in the sera of convalescent COVID-19 patients.

SARS-CoV-2 (COVID-19) Spike S Trimer Recombinant Protein

20-182 0.1 mg
EUR 542.75
Description: The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Rabbit Anti-flagellin protein (Fla/FLGN, S. typhimurium) antiserum

FLGN12-S 100 ul
EUR 469

Recombinant SARS Spike Mosaic S Protein (aa 408-470, 540-573)

VAng-Lsx0056-inquire inquire Ask for price
Description: Recombinant SARS-CoV Spike protein containing 408-470, 540-573 amino acids immunodominant regions was expressed in E. coli and purified by proprietary chromatographic technique.

SARS-CoV Spike Protein

abx060655-1mg 1 mg
EUR 1692

Rabbit Anti-Sm28/Smp28/GST28/GST-mu protein (S. Japonicum, 1-211aa) antiserum

SM282-S 100 ul
EUR 457

Rabbit Anti-S. Pneumococcal Serotype 23F Carbohydrate (Spn23F) Antiserum

SPN231-S 100 ul
EUR 445